Mapping the landscape of viral antibody escape

We screen large mutant libraries of viral proteins for escape from antibody binding/neutralization

https://jbloomlab.github.io/SARS-CoV-2-RBD_MAP_LY-CoV555/

Escape from a single antibody

Escape from lots of antibodies

https://jbloomlab.github.io/SARS2_RBD_Ab_escape_maps/

Binding across the full breadth of a viral family

Binding across the full breadth of a viral family

Binding across the full breadth of a viral family