Brief analysis of spike mutations in XEC SARS-CoV-2 variant

Analysis by Jesse Bloom on Oct-16-2024

 

TLDR: XEC has modest antigenic change relative to KP.2 (current USA-recommended vaccine) and more mild change relative to KP.3.1.1 (current dominant variant), but is not a big antigenic jump

 

Note: this analysis only looks at spike amino-acid mutations, not mutations elsewhere in genome

Brief analysis of spike mutations in XEC SARS-CoV-2 variant Analysis by Jesse Bloom on Oct-16-2024 TLDR: XEC has modest antigenic change relative to KP.2 (current USA-recommended vaccine) and more mild change relative to KP.3.1.1 (current dominant variant), but is not a big antigenic jump Note: this analysis only looks at spike amino-acid mutations , not mutations elsewhere in genome