Allergy in pets

  genetically pre-
disposed condition of hypersensitivity to
common and harmless
substances

Allergy

Outdoor
Seasonal

Indoor
Non-seasonal

Breeds at
higher risk

Allergen-specific
immunotherapy
is the only causal
treatment

Allergen
avoidence

Symptomatic
medication
side effects

Food allergy

Incidence between 10-25% of
dogs with allergic skin disease or 1/3 of dogs with AD

Stronger incidence in dogs
under 1 year or above 6 years

Most common allergens:

beef, chicken, egg, milk,
wheat, soy and corn

Allergy in horses

  genetically pre-
disposed condition of hypersensitivity to
common and harmless
substances

Allergy

With CCD blocking and 2 blocking efficiency detectors

First quantitative multiplex macroarray specifically designed for horses

Expected increase in serological test sensitivity due to a higher concentration of molecular allergens

Over 200 allergen components + extracts included

= lower testing cost per allergen

Fully automated process = higher level of standardization

Identification of ”primary” sensitizing allergens

Identification of allergen cross-reactivities

Selection of relevant allergens for specific immunotherapy

More than
80 allergens
available

Fast result,
in 10-20 minutes

 Concentrations
based on
determination of
threshold values
for reliable result

! Medication that
may affect the
result needs to be
discontinued

Animal becomes
less sensitive or
even insensitive
to allergens

Only causal
treatment for
atopic dogs, cats
and horses

Only licensed ASIT
in Europe*:
product of choice
 

Safe for long-term
treatment:
virtually no
side effects
 

Tailor made for
each individual
patient

®

Dogs

Cats

Horses

75%

70%

84%

_____

_____

_____

This is Diesel
6x Dutch Champion
3 World Championships
2 International
3* Competitions

Don’t let
allergies stop
them from being
champions!

Before

Before

Molecular Allergology: The future of IgE sensitisation detection

With CCD blocking and 2 blocking efficiency detectors

First quantitative multiplex macroarray specifically designed for companion animals

Expected increase in serological test sensitivity due to a higher concentration of molecular allergens

Over 200 allergen components + extracts included

= lower testing cost per allergen

Fully automated process = higher level of standardization

Only 0.5 ml of serum needed

Identification of ”primary” sensitizing allergens

Identification of allergen cross-reactivities

Selection of relevant allergens for specific immunotherapy

For pets with IgE mediated food allergies

(those with immediate reactions after an oral
food challenge)

To help identify patterns of allergen cross-reactivity

To help prioritize the order of oral food challenges

To help identify foods unlikely to cause immediate reactions

Artuvetrin®
Skin Test

More than 80
allergens available

Fast result, in
10-20 minutes

 Concentrations
based on
determination of
threshold values
for reliable result

! Medication that
may affect the
result needs to be
discontinued

TIP

Fluorescein makes
the wheals stand out

Picture: Charlie Walker

When the negative
control is not 0

(negative control +
positive control) / 2 =

Example

Negative control = 6

Positive control = 14

(6 + 14) / 2 = 10 mm

All allergens equal
or higher than
10 mm is positive

Artuvetrin®
Therapy

Animal becomes
less sensitive or
even insensitive
to allergens

Only causal
treatment for atopic
dogs, cats and horses

Licensed ASIT:
product of choice
 

Safe for long-term
treatment: virtually
no side effects
 

Tailor made for
each individual
patient

®

Dogs

Cats

Horses

75%

70%

84%

_____

_____

_____

 Continue a monthly injection interval

1 ml every 4 weeks is standard, but some cases may have better results  with 0.5 ml every 2 weeks
 

Life-long treatment

Increased
symptoms directly
after the injection
which decrease
after 1-2 days

Increased
symptoms
1-2 weeks
before next
injection

lower the dose
for 1-2 injections,
e.g. 0.8 ml

Shorten interval
0.5 ml / 2 weeks
0.8 ml / 3 weeks

A clinically
relevant allergen:

1. is tested positive or
borderline AND

2. is present in the animals
environment AND

3. has a clear relationship
with clinical history

Composing

This is Bob
Bob has symptoms all year

This is Pascal
Pascal has symptoms throughout the year but with increased pruritus during the summer
 

This is Pascal
Pascal has symptoms throughout the year but with increased pruritus during the summer
 

Raising above
the itch threshold:

1. higher allergen exposure

2. secondary infection

3. skin irritation like
fleas, swimming, more or
less washing, etc.
 

Flare-up
 

Find and
prevent the
cause

Sometimes
symptomatic
medication is sufficient

Vicious circle:
non-seasonal
symptoms
 

Pet's Relief®
Products

SKIN CREAM WITH
ZINC OXIDE + 9 HERBAL EXTRACTS

Centella asiatica, Echinacea purpurea, Calendula officinalis,
Hamamelis virgiana, Melaleuca viridiflora, Thuja occidentalis,
Lavendula angustifolia, Salvia lavandulifolia, Arnica montana

ZINC
Cell membrane repair
Cell proliferation
Growth and immune system function

ECHINACEA PURPUREA
Stimulates immune responses
Stimulates fibroblasts cell growth and wound healing process

CALENDULA OFFICINALIS
Antiseptic
Anti-inflammatory and
analgesic properties
Contributes in easing pain

CENTELLA ASIATICA
Inhibits inflammation
Reduces wound oxidative stress
Affects cellular growth and proliferation in injured tissues

HAMAMELIS VIRGINIANA
Strengthens vein elasticity
Stimulates micro-circulation of new-formed tissue
Prevents scar tissue
 

SALVIA LAVANDULIFOLIA
Antiseptic
Analgesic
Sedative and anesthetic activities
 

THUJA OCCIDENTALIS
Antiviral
Anti-inflammatory
Antibacterial properties

MELALEUCA VIRIDIFLORA
It is used for its
anti-microbial effect without irritating sensitive tissues

LAVANDULA ANGUSTIFOLIA
Accelerates wound healing
Formation of granulation tissue
Tissue remodeling
Wound contraction (shrinking)

ARNICA MONTANA
Can be used for sprains, dislocations and rheumatic pain
Anti-inflammatory
Mild analgesic effect
 

Proven efficacy

All components are recognised by studies for their properties

Versatility

Can be applied to any type of superficial injury

Compatibility

Can be used on its own or along side other products

50 and 150 ml bottle

Airless dispenser for easy and hygenic application

Apply at least twice a day
(or with bandage once a day):

1. Clean the injured tissue and skin
(gently wash off crusts first)

2. Apply enough to create a thin protective layer of cream

Hypromellose, poly (vinyl alcohol), citric acid, isopropyl myristate, benzyl benzoate, colloidal silica.

KERAVITA

✔ Natuurlijke ingrediënten

✔ Weinig calorieën

✔versterkt vacht en klauw

✔ Verhoogt de glans van de vacht

✔ Vermindert haaruitval

Verkrijgbaar in tabletvorm

Omega-3

KERAVITA

✔ Natuurlijke ingrediënten

✔ Weinig calorieën

✔versterkt vacht en klauw

✔ Verhoogt de glans van de vacht

✔ Vermindert haaruitval

Verkrijgbaar in tabletvorm

Omega - 3

✔ Sustainable

✔ High EPA and DHA content

✔ High-quality natural fish oil

✔ Vitamin E as an antioxidant

✔ Recommended by veterinarians since 1995

Complementary food for horses, dogs, cats and ferrets

100 caps, 200ml, 500ml, 1L

Pancreatic support

Loyalty & Care program

Free educational
programs

Online news and developments

Newsletter
Website
 

Our specialised staff
are happy to help
you with a case
 

Reminder service
for your practice
Personalised
emails
 

Reminder service
for your clients
App and
Web-reminder

Lunch & Learn

Webinars

DermaTalks

In house days

My allergic pet
sessions