What is a Random Knot?
And Why Do We Care?
Clay Shonkwiler
Knots
A knot is a closed loop in space that can’t be turned into a round circle without breaking it.
Knots
Is It Knotted?
Knots in Nature
Knots in Nature
6UX1A – Carbonic anhydrase II complexed with salicylic acid
Knots in Nature
Knots in Nature
Guiding Question
Knots in proteins aren’t random; do the deviations from randomness tell us something about biology?
Random, You Say
Random?
\(p\)
\(p\)
\(p\)
\(p\)
\(p\)
\(p\)
Random with Constraints
Random with Constraints
Random with Constraints
Random Knots!
