Prenatal development & infancy

Fertilization

  • Sperm & Ovum produced by parents, containing 50% of their DNA.
  • Zygote: a fertilized ovum
    • 23 unpaired chromosomes
    • Dizygotic & Mono zygotic twins
  • Myth of the "passive" ovum
  • "Only 500 eggs" also may be false
  • Gender bias in science
    • Martin, E. (1991). The egg and the sperm: How science has constructed a romance based on stereotypical male-female roles. Signs: Journal of Women in Culture and Society, 16(3), 485-501.

The beginnings of Ontogeny

  • Everyone began life as a single fertilized cell (zygote) which contained our entire genetic code
  • Each of us carries a “genetic code” from our parents
  • This single cell then begins to divide…

Mitosis

  • All body cells (except the sperm and egg)
    • 46 chromosomes in 23 pairs
  • Body cells reproduce by a process called  mitosis
    • (except sperm & egg - meiosis)
  • During mitosis, the cell’s nucleus -including the chromosomes—duplicates itself and the cell divides
  • 2 new cells are formed, each containing the same chromosomes, genes, and DNA as the original cell

Sex and intersex

  • 23rd pair known as "sex chromosomes". XX/XY
    • Y chromosome has sex-determining region Y (SRY) protein
    • X-linked and y-linked
  • XXY: Klinefelter syndrome
  • XO: Turner’s syndrome
  • XXX: Triple X syndrome
  • XYY: XYY syndrome
  • XX SRY-positive karyotype
  • XY: Androgen insensitivity

Stages of Prenatal Development

  • First Trimester (wks 1-12)
    • Zygote wks 1-2
    • Embryo wks 3-8
    • Fetus  wks 9+
  • Second Trimester (wks 13-28)
  • Third Trimester(wks 29-40)

First 2 weeks

Carnegie stages 23 stages of first 56 days

Stage 1 (day 1) fertilization of zygote

Stage 2-4 (days 2-6) cleavage, single cell to embryoblast

Stage 5 (days 7-15) Implantation

The Embryo

Weeks 3-8 aka  days 14-56 aka stages 5-23

First sign of pregnancy at week 6

The Embryo

10-25% of pregnancies

Prenatal Experience

  • Movement
    • hand to mouth, thumb-sucking, kicking, hand-grasping, punching, twisting/rolling, hiccup
  • Tactile Stimulation
    • own activity, twin’s activity
  • Smell
    • odors in amniotic fluid (from mother’s food)
  • Taste
    • Babies taste the amniotic fluid; develop early preference for flavors in the fluid (from mother’s food)

 

Prenatal Experience

  • Hearing
    • Voices – rhythm, pitch & prosody (rise and fall)
    • Music
    • Heartbeat
    • Stomach growling
  • Vision
    • Open eyes at 28 weeks
    • some bright sunlight can filter through the womb
    • can see dim shapes at 33 weeks
    • vision is the last sense to develop

 

Prenatal Learning & Development

 

  • Prenatally, children come to prefer familiar tastes and sounds
  • Newborns recognize the auditory patterns of speech, rhythm and prosody of the language spoken around them
    • Babies are born crying in the intonation of their culture’s language
    • Study with French vs. German babies
  • Newborns prefer their mother’s voice to other voices, and prefer stories read by mother while they were in the womb!

 

Teratogens: Harmful environmental influences

  • Prescription/OTC Drugs
    • Aspirin, Caffeine, Thalidomide
  • Nicotine
  • Alcohol & other Drugs
    • Fetal Alcohol Syndrome (FAS)
  • Radiation
  • Pollution
  • Lead
  • Disease
    • HIV, parasites, chicken pox

Socioeconomic factors

  • 16% US children born into poverty (2017, record low)
  • 10% Adults uninsured
  • w/o insurance, childbirth alone coasts $10,000+
    • Full pregnancy can costs up to $250,000
  • Poverty threatens prenatal and postnatal development
    • Poorer nutrition
    • Less resources
    • Increased stress
    • Negative interactions
    • Incarceration

Childbirth

  • Human children are born “earlier” (less mature) than other animals because:
  • Upright walking humans have smaller pelvises than apes
  • Human children have large heads & brains

 

Newborn reflexes

  • eye blink
  • Rooting/Sucking Reflex
  • Moro Reflex
  • Palmar grasping Reflex
  • Stepping Reflex
  • Babinski Response
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