March 16, 2015
iPQB Journal Club
weighted regression by county population (squareroot maxed to 250k)
Were the entire United States situated at the elevation of San Juan County, CO (3,473 m), we estimate 65,496 99% CI [46,855–84,136] fewer new lung cancer cases would arise per year (ceteris paribus and assuming 2000-census county-populations).
Finally, following previous analyses, we used lung cancer as the indicator of accumulated population exposure to smoking. This adjustment for lung cancer in multivariable regressions may have overadjusted, if altitude has a beneficial effect on lung cancer. (Ezzati et al. 2012)
Ed Yong Tweet