July 15, 2016
White Paper: Oct 31, 2008
Network Release: Jan 2009
Preprint only
1142+ citations on Google Scholar
Chain of ownership through digital signatures
Valid transactions are collected into blocks by miners
Before the block has been solved, those transactions are considered unconfirmed.
Proof of Work & the Blockchain
Miners try nonces until they find a block hash starting with many zero bits
Each block is built on top of a preceding block
In case of a tree, chain with that took the most work to create is adopted by the network.
AUROC of proximity on the 402 known drug-disease pairs as positives and 18,162 unknown drug-disease pairs as negatives
Open access citation advantage by field (literature compilation)
(fold change)
DOI: 10.7554/eLife.16800