Efficacy of anticoagulation after knee arthroscopy/lower leg casting

Title Text

  • Two randomized, open-label, blinded outcome evaluation trials.
  • 1,543 Patients undergoing knee arthroscopy (POT-KAST) or lower-leg casting (POT-CAST) were randomized to receive either low molecular weight heparin (731) or no anticoagulation (720) for 8 days post arthroscopy/duration of casting.
  • Outcome measure: symptomatic venous thromboembolysm and major bleeding 3 months after the procedure.

 

Study protocol

Results

Results

Conclusion

Prophylactic anti-coagulation with low-molecular-weight heparin after knee arthroscopy (8 days) or during immobilization due to casting (whole period) is not effecttive for prevention of VTE.

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