Low-Dose CT Screening for Lung Cancer: Computer-Aided Detection of Missed Lung Cancers
M. Liang, et al.
Journal Club 1/31/17
Jason Hostetter, MD
Introduction
Introduction
Methods
Methods
Methods - Image review
Methods - CAD systems
Methods - CAD performance
Statistics
Results - Cancer characteristics
Reviewers: moderate - substantial agreement
Avg 4.8 → 11.4 mm
Results - CAD detection
Results - CAD detection of actionable nodules at time 0
Of 37 actionable cancers:
CAD 1: 62%
CAD 2: 84%
CAD 3: 70%
CAD 4: 70%
Results - False positives at time 0
Results - CAD Detection of Cancers at time 1
Results - CAD Matchup
System | Time 0 Sens | Time 1 Sens | FP |
---|---|---|---|
CAD 1 | 56% | 74% | 7.4/scan |
CAD 2 | 70% | 82% | 1.7/scan |
CAD 3 | 68% | 82% | 0.6/scan |
CAD 4 | 60% | 78% | 4.5/scan |
Discussion
Limitations
Conclusion
My thoughts