riza@thehyve.nl
@rizanugraha
Data warehouse bringing together scientists from clinical sciences, preclinical research and discovery – around the data
Combination of internal datasets & documents with public datasets & knowledge
Tailored to both biologists/clinicians & bioinformaticians
Dual nature: in use for translational research in both pharma & hospitals/clinics
clinical data
biomarker
contextual info
tranSMART
biochemical observations
dosing
adverse events
demographics
outcomes
elisa/rbm
snp/cnv
'omics'
genomic
pathways
genomics/sequence
protein functions
literatures
ETL/CURATION
ETL/CURATION
ETL/CURATION
INFORMATION STANDARS: 1) ONTOLOGIES, TAXONOMIES, VOCABULARIES 2) SYNTACTICAL STANDARDS
mining
search
open source - GPLv3
+100 computer scientists, physician scientists
community driven
+150 downloads by academic, industrial, governmental, and private research
multiple collaborations between non-profits, academic medical centers, pharmaceutical companies, and commercial groups.
2009
2012
2013
2014
2015
J&J, Recombinant
Open Source!
v1.1
v1.2
v1.3
v2.0 ?
login: guest/transmart2015
+ Genome Browser
+ tranSMART Installer
+ proteomics support
+ metabolomics support
+ RNASeq data
+array CGH data
+ RESTful API
+ RClient
+ Core API
+ tranSMART Batch
+ many more ..
+ many more ..
Hackathons
Trainings
Seminars
Conferences
User groups
Wiki
annual meetings
Posters
Speakers
Boston
London
Paris
Amsterdam
annual meetings
Hackathons
Speakers
October 19-21, 2015 in Amsterdam at the Netherlands Cancer Institute.
Modular architecture, responsive, interactive, better performance
Audit Logging, SNP, GWAS Improvements, Advanced Analysis Improvements
TranSMART REST-API
Analytical Tools
(RShiny, OpenCPU)
UI Client
transmart-base-ui
MobileApp
3rd party
oAuth
oAuth
oAuth
oAuth
VU MC
Imperial College
TranSMART REST-API
VU MC
CrossfilterJS
DC.JS
DC.JS