ECP Update

5/26/21

 

Stephen

New Pre-processed data

  • Did the group average matrices change?
  • Are nearest neighbor classifiers any better?
  • The average correlation between a HC's previous connectivity matrix and the new one is .8735
  • The correlation between the average HC matrices is .9784

Repeat Last Finding

  • Repeated statistic analysis from previous paper
  • Two TLE subjects didn't make the cuttoff in Joe's new pipeline :( 

The result was no change.

$$r^2=.95$$

Nature Protocol

  • Just followed the figure
    • Used F-test on each edge for 4 categories (HC, L,R, Bi)
    • Converted F-test to p value

pValue Distribution

Result

Notes

  • Unable to do "CWAS" type as don't have patient drug info

Cameron's T-maps

  • One of the questions of regarding the use of a mask is how consistent are the masks across folds?
  • I used 5 fold cross validation on the new data. Used 1,000 permutations per fold to estimate corrected t-values
  • Then visualized on each node by summing t-values

Left

Relative to

Control

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