Predicting DDI among unexplored pairs
Vivek Sethia
Motivation
Drug Developmental Issue
- Development Cost
- Development Time
- Processes involved
Drug Repurposing
Current Implementations
- Corpus of DDI from different sources
- Signal Detection Algorithm using FAERS from FDA
- Different tools available
- Interaction Checker
- ksRepo, Cogena (based on genes)
Implementation
- Creating a new dataset of ADR along with already available data
- Implementing a technique to predict DDI
- Using the technique to infer positive DDI
Datasets Available
- DrugBank
- FDA
- Medlink
- DrugDex
- TwoSide