New approaches to old ideas..

Drivers of medical innovation

From "pharma" to "computation"

From "pharma" to "computation"

Technical design debt

Technical design debt

• The "kernel" is almost vanishingly small
• Supporting structure and software systems
  • Always underestimated
  • Critical importance
• Deployment environment

Promise of computation

Promise of computation

• Explore complex solution spaces
  • Quickly
  • Efficiently
• Imaging informatics/analytics
• Data integration
• Genomics
• Molecular folding

The reality of computation

The reality of computation

• There is no such thing as a free lunch
• Commodity solutions do not replace domain knowledge
• Quick and "sexy" is not the same as deep solutions
• Core understanding of the problem and solution are the real keys

Why do they look so bad?

• Bad design paradigms
• No competition
  • Closed source
  • Locked to a device
• Core conservative philosophy

How to apply these ideas?

How to apply these ideas?

What about research apps?

• What do they do?
• What is the development cycle?
• What is the deployment cycle?

Sampling of what we do...

Skeletal Survey Report Tool

"Old Way"

"Old Way"

New way

Normative image reference

http://fnndsc.childrens.harvard.edu/library-anon

ChRIS

Thank you!