Welcome

Back!

This course is different!

No Project!

Hands-on Knowledge + Research

Be a Biomedical

3rd oldest Hospital in the US

$1+ billion research program 

largest in the world

6th best Hospital in the US

5th best place to work in MA (2017)

$630+ million research program 

2nd largest in the world

13th best Hospital in the US

also a good place to work :)

are part of

New imaging complex at Assembly Row

~1000 Biotech companies in Boston!

All universities have some biomedical research going on!

This course prepares       

for a career in biomedical research and life sciences!

My name is

Daniel Haehn

Ham

n

This is my favorite!!!

Tu / Th

Class 11:00a - 12:15p

Office Hours 9:30 - 11:00a

Tu / Th

40 Lectures

Knowledge + Hands-on

Kai Kang, MS, MD, PhD

Etiometry, Inc.

Jayender Jagadeesan, PhD

Brigham and Women's Hospital

Rudolph Pienaar, PhD

Boston Children's Hospital

Michal Depa, MS

Stata Diagnostics

Mike Halle, PhD

Harvard Medical School

Nicholas, Leotta MS

City College of New York

7 Assignments

ECG, EEG/MEG, US, X-ray, EM/LM, CT, MRI/fMRI, SPECT/PET

10 Quizzes

via Blackboard

Intro to Research

How to read a paper

How to write a paper

+ 10 Sessions

Participation

counts 20%!

40 Lectures

 

7 Assignments (30% of final grade, plus 10% bonus)

 

10 Quizzes (20% of final grade, take-home through blackboard)

 

Journal Club (30% of final grade)

 

Participation (20% of final grade)

Blackboard

Slides + Videos

Quizzes

Announcements

 

https://umb.umassonline.net/

Syllabus

Continuous Signal

Analog

Infinite Accuracy and Infinite Measurements

Electrical Signals

Mechanical Signals

Hydraulic Signals

Optical Signals

Chemical Signals

Electrical Potentials/Activity like ECG, EEG..

Vibrations such as Mechanomyogram (MMG)

pH measurement, urinalaysis (UA), blood glucose, electrolyte levels, cholesterol..

blood vessel wall shear stress

some imaging methods (X-ray, NIRS..)

blood pressure?

Accustical Signals

blood pressure.

Sensors

Analog

Sensors

Digital

Analog to Digital Converter (ADC)

Continuous Signal

Analog

Infinite Accuracy and Infinite Measurements

Discrete Signal

Digital

Limited Accuracy and Limited Measurements

From Analog...

...to Digital

Distortions

Sampling Limitations

Noise

Sampling

Analog

Sampling Rate

Samples per second [1/s]

Hertz [Hz]

Analog Signal

2 Samples per second

0

1

time [s]

6 Samples per second

10 Samples per second

6 Hz

10 Hz

2 Hz

Aliasing

Original Signal

Sampled Points

Reconstructed Signal

Sampling Rate too low

A higher sampling rate is better

?

2 Floats

6 Floats

10 Floats

It's a trade-off!

Nyquist-Shannon Theorem

sampling frequency > 2x signal frequency

guarantees perfect reconstruction

What does that mean? And how do we get the signal frequency?

Fourier Analysis

Intro to Research

How to read a paper

How to write a paper

+ 10 Sessions

CS666 Lecture 1

By Daniel Haehn

CS666 Lecture 1

Slides for CS666 Biomedical Signal and Image Processing at UMass Boston. See https://cs666.org!

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