Addressing Measurement Invariance in Scales for PTSD Using Nonlinear Latent Variable Models

Veronica T. Cole

Center for Developmental Science, UNC-Chapel Hill

Department of Psychology, Wake Forest University

Symposium Title
Confirmatory Factor Analysis Models of PTSD:
A Critique and Some Best Practice Suggestions

Agenda

  • A brief introduction to measurement invariance
  • Why should PTSD researchers care about measurement invariance?
    • General consequences
    • Measurement invariance in PTSD
  • Modeling measurement using nonlinear factor models
  • The Galveston Bay Recovery Study
  • A brief introduction to measurement invariance
  • Why should PTSD researchers care about measurement invariance?
    • General consequences
    • Measurement invariance in PTSD
  • Modeling measurement using nonlinear factor models
  • The Galveston Bay Recovery Study

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Confirmatory factor analysis

A key assumption

When we measure a latent variable with a set of items, these items measure the latent variable equally well for all subjects.

E\left(y_{ij}|\eta_i\right) = E\left(y_{ij}|\eta_i, \textbf{x}_i\right)

Millsap, 2012; Meredith, 1993

HACK : WRITING ::

TRUANT : SCHOOL

THIEF : PROPERTY

MERCENARY : WARFARE

CRIMINAL : FELONY

DEFENDANT : ACCUSATION

Curley & Schmitt, 1993

Example: SAT Analogies

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Configural measurement invariance

Meredith, 1993

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Weak metric invariance

Meredith, 1993

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Strong metric invariance

Meredith, 1993

  • A brief introduction to measurement invariance
  • Why should PTSD researchers care about measurement invariance?
    • General consequences
    • Measurement invariance in PTSD
  • Modeling measurement using nonlinear factor models
  • The Galveston Bay Recovery Study

(Why) do PTSD researchers care?

In order for the assumption of measurement invariance to be a concern for PTSD researchers, there needs to be evidence that...

  • violations of this assumption undermine the validity of inferences in latent variable models
  • this assumption is violated in current indices of PTSD

(Why) do PTSD researchers care?

In order for the assumption of measurement invariance to be a concern for PTSD researchers, there needs to be evidence that...

  • violations of this assumption undermine the validity of inferences in latent variable models
  • this assumption is violated in current indices of PTSD

Consequences of Violating MI Assumption: In Theory

In the absence of...

  • configural invariance: no between-groups comparisons of any kind are possible.
  • weak metric invariance: no between-groups comparisons of factor variances or covariances are possible.
  • strong metric invariance: no between-groups comparisons of factor means are possible.

Meredith, 1993; Widaman & Reise, 1997; Vandenberg & Lance, 2000

Consequences of Violating MI Assumption: In Practice

  • Configural invariance is absolutely necessary.
  • Partial weak and strong metric non-invariance may be tolerable.
    • Equivocal findings about unmodeled effects
      • Factor score estimates are unbiased in some cases
      • More severe bias in regression coefficients
    • We will discuss methods of directly accommodating measurement non-invariance

 

Byrne, Shavelson, & Muthén, 1989; Chalmers, 2016; Curran et al., 2016, 2018

(Why) do PTSD researchers care?

In order for the assumption of measurement invariance to be a concern for PTSD researchers, there needs to be evidence that...

  • violations of this assumption undermine the validity of inferences in latent variable models
  • this assumption is violated in current indices of PTSD

(Why) do PTSD researchers care?

In order for the assumption of measurement invariance to be a concern for PTSD researchers, there needs to be evidence that...

  • violations of this assumption undermine the validity of inferences in latent variable models
  • this assumption is violated in current indices of PTSD

Measurement Invariance in PTSD

  • Males vs. females
    • Minor non-invariance between male and female veterans
    • More substantial non-invariance across male and female survivors of a broader range of traumas
  • Original vs. translated measures
    • Some evidence that Spanish and English versions of PCL-C  show metric invariance
    • Minor differences in items, not consequential at scale level
  • Older vs. younger
    • Particularly between age groups of children and adolescents

 

King et al., 1995; Chung & Breslau, 2008; Marshall, 2004; Orlando & Marshall, 2002; Miles et al., 2008; Contractor et al.,2013

Measurement Invariance in PTSD

  • Military deployment
    • DTC is invariant across veterans from pre-Vietnam, Vietnam, and Iraq/Afghanistan
    • Weak metric invariance for PCL in deployed vs. non-deployed
  • Country of origin
    • ​Configural, but not metric, invariance of the HTC across asylum seekers from different global regions
    • General factor structure assessed in a few refugee samples
      • US-resettled refugees of Khmer Rouge
      • Refugees from civil war in Sierra Leone, 2001-2006

 

McDonald et al., 2008; Mansfield et al., 2010; Rasmussen et al., 2016; Palmieri et al., 2007; Vinson & Chang, 2012

  • A brief introduction to measurement invariance
  • Why should PTSD researchers care about measurement invariance?
    • General consequences
    • Measurement invariance in PTSD
  • Modeling measurement using nonlinear factor models
  • The Galveston Bay Recovery Study

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Directly modeling measurement non-invariance

Moderated nonlinear factor analysis (MNLFA) allows measurement parameters to be linear functions of the parameters, thus accommodating both impact and measurement non-invariance.

$$E\left(y_{ij}|\eta_i, x_{ip}\right) = g^{-1}\left(\lambda_{ij}\eta_i + \nu_{ij}\right)$$

$$\lambda_{ij} = \lambda_0 + \lambda_p x_{ip}$$

$$\nu_{ij} = \nu_0 + \nu_p x_{ip}$$

$$\eta_i \sim \left(\alpha_i,\psi_i\right)$$

$$\alpha_i = \alpha_0 + \alpha_p x_{ip}$$

Bauer & Hussong, 2009; Bauer, 2017

Automated MNLFA

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Gottfredson et al., 2018; Cole et al., 2018

  • Used a data-driven search procedure to test each covariate for measurement non-invariance and impact.
  • Procedure iterates through multiple models containing different combinations of measurement non-invariance
  • Implemented via R package aMNLFA now on CRAN.

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Automated MNLFA

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...

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$$x_{i1}$$

Gottfredson et al., 2018; Cole et al., 2018

  • Used a data-driven search procedure to test each covariate for measurement non-invariance and impact.
  • Procedure iterates through multiple models containing different combinations of measurement non-invariance
  • Implemented via R package aMNLFA now on CRAN.

$$x_{i2}$$

.

.

.

$$x_{iP}$$

Automated MNLFA

$$y_{i1}$$

$$y_{i2}$$

$$y_{iJ}$$

...

$$\eta_{i}$$

$$x_{i1}$$

Gottfredson et al., 2018; Cole et al., 2018

  • Used a data-driven search procedure to test each covariate for measurement non-invariance and impact.
  • Procedure iterates through multiple models containing different combinations of measurement non-invariance
  • Implemented via R package aMNLFA now on CRAN.

$$x_{i2}$$

.

.

.

$$x_{iP}$$

Automated MNLFA

$$y_{i1}$$

$$y_{i2}$$

$$y_{iJ}$$

...

$$\eta_{i}$$

$$x_{i1}$$

Gottfredson et al., 2018; Cole et al., 2018

  • Used a data-driven search procedure to test each covariate for measurement non-invariance and impact.
  • Procedure iterates through multiple models containing different combinations of measurement non-invariance
  • Implemented via R package aMNLFA now on CRAN.

$$x_{i2}$$

.

.

.

$$x_{iP}$$

Automated MNLFA

$$y_{i1}$$

$$y_{i2}$$

$$y_{iJ}$$

...

$$\eta_{i}$$

$$x_{i1}$$

Gottfredson et al., 2018; Cole et al., 2018

  • Used a data-driven search procedure to test each covariate for measurement non-invariance and impact.
  • Procedure iterates through multiple models containing different combinations of measurement non-invariance
  • Implemented via R package aMNLFA now on CRAN.

$$x_{i2}$$

.

.

.

$$x_{iP}$$

  • A brief introduction to measurement invariance
  • Why should PTSD researchers care about measurement invariance?
    • General consequences
    • Measurement invariance in PTSD
  • Modeling measurement using nonlinear factor models
  • The Galveston Bay Recovery Study

Galveston Bay Recovery Study

  • Study of experiences following Hurricane Ike, which hit the Galveston Bay on 9/13/2008
  • N = 656 adult residents of Galveston and Chambers Counties
  • First measured between 2 and 5 months after the hurricane
  • Demographics
    • 15.5% Black; 11.1% Hispanic/Latinx
    • 59.9% Female
    • 38.3% over 55

PCL-C Re-Experiencing

  • The PTSD Checklist Civilian Version (PCL-C) was administered at all three assessments
    • Only considering the first time point here
    • PCL-C pertains to "most traumatic" experience of subject's life
  • Here we consider the re-experiencing factor due to its relatively stable structure
  • Items assessed how much a given symptom bothered subject
  • Measured on a five-point scale
    • Not at all
    • A little bit
    • Moderately
    • Quite a bit
    • Extremely
  • Final sample: N = 512

PCL-C Re-Experiencing

How much were you bothered by...

  • Repeated, disturbing memories, thoughts, or images of this stressful experience?
  • Repeated, disturbing dreams of this stressful experience
  • Suddenly acting or feeling as if this stressful experience were happening again, as if you were reliving it?
  • Feeling very upset when something reminded you of this stressful experience?
  • Having physical reactions, for example, heart pounding, trouble breathing, sweating, when something reminded you of this stressful experience?

Analytic strategy

  • Maximum likelihood for categorical outcomes
    • Standard fit statistics not available
    • Use WLSMV to test model without covariates
      • Unidimensional model with one residual covariance showed adequate fit, \(\chi^2(4) = 19.328, RMSEA = .086, CFI = .99, TLI = .99)\)
  • Accounted for complex sampling
    • Subjects sampled from 77 segments in 5 strata, rated from most to least hurricane damage
    • Sampling weights used in all analyses
  • Three covariates: self-reported gender (male vs. female); age group; race/ethnicity

Memories

Re-Experiencing

Dreams

Reliving

Upset when Reminded

Physical Reaction

Male

Black

Hispanic

Age

Final Model

Memories

Re-Experiencing

Dreams

Reliving

Upset when Reminded

Physical Reaction

Male

Black

Hispanic

Age

Age Non-Invariance: Memories

Gender Non-Invariance: Dreams

Conclusions

These results underscore an important rule about measurement non-invariance:

 

\[ \neq \]

statistically significant

practically meaningful

As in many of the prior studies, measurement non-invariance here likely would not cause scale scores to be particularly biased.

Conclusions

These results underscore an important rule about measurement non-invariance:

 

\[ \neq \]

statistically significant

practically meaningful

However...

  • The age effect may be worthy of further investigation
  • This group was largely homogeneous with regard to trauma type, so results may be stronger for others
  • Potential confounding of memory and PTSD symptoms?
    • This could be an interesting problem for explanatory IRT.

De Boeck & Wilson, 2004

Acknowledgements

Susan Ennett

Nisha Gottfredson

Andrea Hussong

Dan Bauer

Patrick Curran

Funding

F31 DA040334 (Fellow: Cole)
T32 HD007376 (PI: Hussong)
R01 DA034636 (PI: Bauer)
R01 DA037215 (PI: Hussong)

Thank you!

colev@wfu.edu

 

PTSD APS 05262019

By Veronica Cole

PTSD APS 05262019

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