JUNE

Joseph Bullock, Carolina Cuesta-Lazaro, Arnau Quera-Bofarull, Miguel Icaza-Lizaola, Aidan Sedgewick, Henry Truong, Aoife Curran, Edward Elliott, Richard Hayes, James Nightingale, Tristan Caulfield, Kevin Fong, Ian Vernon, Julian Williams, Richard Bower and Frank Krauss

Outline

Motivation for new Covid-19 model
Main model components:
- Virtual population
- What can residents do in JUNE?
- Modelling and mitigating infection
Tuning the model
How does JUNE differ from other models?
Preliminary results

The questions JUNE would like to answer

Understanding the geographical spread of the disease
What measures need to be taken to end national lockdown situations safely, and how effective are local/regional lockdowns?
What are the most effective measures to be taken to not overwhelm NHS capacity?

We need an accurate model of the UK's geography and demography to answer these questions!

Virtual population: a "digital twin"

Use 2011 Census information
What defines a JUNE "resident"?
- age (27)
- sex (f)
- ethnic group (Caribbean)
- deprivation index 2 (1-10)
- household composition
- work sector / subsector
  (healthcare/doctor)
- mode of transport (public)
- area of residence
- area of work

(From Nomis census service)

London

North East

June's Demography

male

female

male

female

What can residents in JUNE do?

Residence
- Care Home
- Household
Primary activity
- Company
- Hospital
- School
- Care Home
- University

Travel
- Commute
- National Travel
Leisure
- Shopping
- Pubs/restaurants
- Cinema
- Residence visits

Modelling and mitigation infection

Model the spread of the infection as related to:
- strength of interaction in a given venue
- proportion of infected venue occupants, and how infectious they are
- number of contacts experienced in a given venue, and length of time
'Policy' interventions to reduce the spread of the infection
- Close schools, except for children of key workers

Tuning the model

Tunable parameters?
- ~10 interaction strengths
- Infection seeding strength
- Proportion of asymptomatic cases
- Policy "interaction strength" reduction
- ...
Very expensive model to evaluate!