Architecting and Building the Future of Healthcare Informatics: Cloud, Containers,

Big Data and CHIPS

 

Rudolph Pienaar, PhD

 

 

Technical Director
Fetal-Neonatal Neuroimaging and Developmental Science Center


Staff Scientist
Boston Children's Hospital
 


introduction

Healthcare informatics is at an inflection point and is perhaps ill suited to handle the information tsunami

This talk considers some of the patterns in information flow - both historical and trending

  • Data portability
  • Compute portability, i.e. containers
  • Big Data

introduction

and offers one particular solution we have developed called...

Cloud

Healthcare

Information

Processing

Service

CHIPS


overview

to guess at the future...

you have to understand the present

Carl Sagan

you have to know the past 

to understand the present




















overview


Information explosion...

Healthcare


Information explosion...

Healthcare

  • 1.65M tumors measured in various modalities
  • > 4 exabytes of data in various localities
  • 1 petabyte of data (0.001EB) to transfer 
  • On current Internet, would take about 21 days to transfer this data around.

healthcare... philosophy shapes informatics

historically, healthcare is differential, not integrative

informatics is poorly understood and not seen necessarily as fundamental

classically information relationship is best described as 1:1

the practice of medicine is less integrative


healthcare "compute"...

provided by vendors with very specialized skills and market

thin, vertical stacks


Typical hospital "web" apps...


Typical hospital "web" apps...


Typical hospital "web" apps...


silos...

Multiple, deep data sets exist in the healthcare dataverse

Largely disconnected and independent of each other

clinical

billing

health records


patterns of information flow in healthcare

Current

  • Unidirectional
  • Isolated
  • Non-integrative
  • Static

Future


patterns of information flow in healthcare

Current

  • Unidirectional
  • Isolated
  • Non-integrative
  • Static

Future

  • Multi-directional
  • Collaborative
  • Integrative
  • Dynamic

medical compute... in the cloud

definite need for data mobility and centralization...

with compute being "free" to process data where-ever it might naturally collect...


CHIPS...

CHIPS is a bio-medical data workflow manage that allows easy and intuitive collection, analysis, and sharing of data between parties.

  • allows for advanced view rendering
  • allows for sharing of images
  • allows for immersive real time collaboration
  • allows for post-processing of images

many data sources... many compute sources...

via here

connect data here

to here...

and compute!


containerization


security

  • Medical data is constrained by many external factors


     
  • Logging and control
  • Single shutoff point

     
  • Communication pathways
  • HIPAA
  • Local regulatory
  • IRB

secure architecturally


big data

  • Imaging


     
  • Genomics
  • Pathology
  • Input DICOM space
  • Processed result space
  • Structured clinical reporting

big data...


UI concepts


conclusion

  • Healthcare compute is at an inflection point
  • Lags larger computing -verse
  • Many opportunities and challenges exist

Untapped opportunity to integrate cutting edge approaches to inform healthcare


references... CHIPS/ChRIS

  • https://github.com/FNNDSC/ChRIS_ultron_backEnd
  • https://github.com/FNNDSC/ChRIS_ultron_frontEnd
    

references... services

 
  • https://github.com/FNNDSC/viewerjs
  • https://github.com/FNNDSC/gcjs
  • https://github.com/FNNDSC/fmjs
  • https://github.com/FNNDSC/toolbarjs
  • https://github.com/FNNDSC/rboxjs
  • https://github.com/FNNDSC/rendererjs
  • https://github.com/FNNDSC/thbarjs
  • https://github.com/FNNDSC/pman
  • https://github.com/FNNDSC/pfioh
  • https://github.com/FNNDSC/pfcon

references... viewers

  • https://goxtk.com
    
  • https://github.com/FNNDSC/ami

team

  • Jorge Bernal
  • Nicolas Rannou
  • Rudolph  Pienaar
  • Yangming Ou
  • Daniel Haehn
  • Daniel Ginsburg
  • Ellen Grant

BCH Team

BU Team

  • Orran Krieger
  • Ata Turk
  • Aditya Awalker

RedHat

  • Dan McPherson
  • and others!

fin!

Thank you!

FTC_2017-12min

By Rudolph Pienaar

FTC_2017-12min

Future Technology Conference 2017

  • 931