Jesse Bloom PRO
Scientist studying evolution of proteins and viruses.
Jesse Bloom
Fred Hutch Cancer Research Center
Howard Hughes Medical Institute
Twitter: @jbloom_lab
These slides are available at https://slides.com/jbloom/challenge-seattle-2021
Ability of human serum collected in 1985 to neutralize isolates of CoV-229E from subsequent years. See this Twitter thread for details.
Mutations that affect recognition by human sera. Tall letters mean mutation reduces binding by serum antibodies. See this Twitter thread for details.
Mutations at site 484 are present in isolates from various countries, and have arisen multiple times. See this Twitter thread.
For my personal guess, see here.
By Jesse Bloom
Scientist studying evolution of proteins and viruses.