Mapping the landscape of viral antibody escape

We screen large mutant libraries of viral proteins for escape from antibody binding/neutralization

Escape from a single antibody

Escape from lots of antibodies

Binding across the full breadth of a viral family

Binding across the full breadth of a viral family

Binding across the full breadth of a viral family

Crowe-DARPA-brainstorming

By Jesse Bloom

Crowe-DARPA-brainstorming

Crowe lab brainstorming session for DARPA grant

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