Why Quantum Computers?

• Computation: Since quantum bits or qubits can exist in both states 0 and 1 as compared to a classical computer which can only exist either 0 or 1, the computation capabilities for a quantum computer is exponentially increased.
• Quantum Search: The potential of quantum computers has taken a leap to understand problems in a given search space.
• Solving Optimisation problems
• Quantum Cryptography

Trial Success Metric System

• Key Feature of the TPO. It helps in predicting the likelihood of a Trial being successful will be hugely beneficial during Trial Design.
• New MIT Study Puts Clinical Research Success Rate at 14%. Only 14% of all drugs in clinical trials eventually win approval from the FDA 
• Several factors which affect this include :
  • Recruiting patients: Finding the right patient for a clinical trial. An increase in attrition rates of patients during a trial is also high.
  • Lack of Infrastructure or Sites
  • This further leads to lower chances of the drug reaching the market.

Data Used 

• Data used: 3k Citeline trial data that focuses on Oncology Leukemia. Input Parameters considered were Trial_phase (categorical), sponsor_academic (1 or 0), sponsor_cooperative_group (1 or 0), sponsor_government (1 or 0), sponsor_industry (1 or 0), sponsor_not_for_profit_funding_entity (1 or 0), sponsor_top_20_pharma (1 or 0), sponsor_all_other_pharma (1 or 0 )

• Output : Whether the trial would be successful or not-i.e. can be either 0 or 1 .

Demo

Advantages​ of this Method

• Tapping one of the most technologically advanced computing technique: Quantum Computing
• QC took less than 30 seconds to train for 4 Epochs as compared to Classical Computer which takes more time
• First application of Quantum for Clinical Trials (as per our research)
• Train on Classical and Quantum Computer simultaneously
• Further work could be done in understanding clinical drugs, drug-drug interaction and drug discovery