Pre-start

Announcements

  • Assignment philosophy...I was told by my superiors "Shay can do things however he feels most comfortable"
    • Mistakes + corrections = learning
    • Mistakes + no incentive to make corrections = punishment? 
      • Not sure how this promotes learning or trying new things?
    • Slide below!
  • Homework 2...
    • Comments! Here for questions & CONCERNS! :)
  • Homework 3: https://elec548.github.io/Assignments/hw3.html
  • Final Project comments!

Example!

  • Problem 2c of homework 2
    • Multiple ways to do it as long as it's justified and clearly explained; however, a given and expected answer that's most commonly done which is what people would look for MAY NOT be the only one!
  • Homework 2 plotting tuning curves & fano factors (idk about vals)

Neural Signal Processing & Machine Learning

ELEC/BIOE 548 | ELEC 483

Fall 2022

Episode 14: Finish Classifying! Perhaps begin clustering things?

1

Introduction. Class & brains

2

Fundamental neurobiology. How do neurons fire? How/what do we record?

3

Modeling spike trains. First bit of analysis work and understanding firing properties of neurons.

5

Classification. Making machines learn. Which direction is a monkey trying to reach? Bayesian decoding.

4

Point processes. Continued modeling work of neurons.

6

Clustering/Mixture models. Making machines learn some more. Spike sorting.

Bi-weekly Schedule

7

Continuous decoding. Kalman filters. Machines continue to learn.

8

Spectral analysis? LFP interpretation in spectral domain. But also kinda in clustering.

Brain Signals!

  • How can we measure neural activity?

  • What info do neurons encode in trains of action potentials (“spike trains”)?

  • How can we model “statically” encoded information?

  • Estimation/”decoding”

  • Signal conditioning – “spike sorting” (PCA, Expectation-Maximization)

  • How can we model/decode “dynamic” information? (filtering, Kalman, HMM)

  • Beyond spike trains (LFP, EEG, imaging)

The Journey

  • Recognizing patterns and making machines learn!
    • Chapter 4. Classification!

Monkey Reach Task

K = num targets/classes

N = num trials

D = num neurons

\((x_n)_d!\)

ELEC548 Lec14

By Shayok Dutta

ELEC548 Lec14

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