Due Tonight!

Assignment 5

PyDicom

load CT volume, slice it, adjust window/level

coming soon!

The AMIGO Suite

Jayender Jagadeesan, PhD

Harvard Medical School

Mahsa Geshvadi

Magnetic resonance imaging

MRI

Magnet

Extremely Powerful

Always On!

1.5 Tesla

3 Tesla

7 Tesla

60,000x stronger than earth magnetic field

$6.5 million

Coils

to enhance contrast

Image Volumes

Voxel size for CT: 0.625-1.25 mm^3

similar to MRI

0.1-1 mm^3

Dr. Raymond Damadian's Indomitable (1977)

Sir Peter Mansfield (1973)

+ Paul Lauterbur

Magnet

Radio Frequency

Gradient Coil

Electro-Magnetic Field

cuts large Magnetic Field into

smaller sections

stimulates atoms

Hydrogen Atoms (Water + Fat)

specific frequency of resonance is called the Larmour frequency

Different tissues (such as fat and water) have different relaxation times

Magnet

RF Pulse

Echo Time (TE)

Repetition Time (TR)

different per tissue!

Fourier Transformation

snapping back

Structural MRI

Structural MRI

MRI Physicist develops sequences

Diffusion Weighted Imaging (DWI)

Motion of water molecules

White Matter Pathways

Approximation!

DTI

fMRI

functional MRI

localized brain activity

Magnetic resonance angiography (MRA)

Aneurysm

Stenosis

brain tumor

  • Tumors
  • Inflammation
  • Certain organs’ blood supply
  • Blood vessels

Gadolinium

Contrast Agent

MRI $2000

CT $1200

10 mins

1 hour

better contrast

super noisy

  • An IUD
  • Artificial joints
  • A pacemaker
  • Eye implants
  • Aneurysm clips
  • Shrapnel
  • Orthopedic hardware
  • Dark tattoos

MRI: Risk

The AMIGO Suite

Is an MRI in there?

Jayender Jagadeesan, PhD

Harvard Medical School

Mahsa Geshvadi

CS666 Lecture 17b

By Avanith Kanamarlapudi

CS666 Lecture 17b

Slides for CS666 Biomedical Signal and Image Processing at UMass Boston. See https://cs666.orghttps://cs666.org

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