Hematuria
408510095 陳明皓

Immunoglobulin A
Expressed in mucosal tissues.
Forms dimers after secretion.
Constitutes only 10-15% of the total immunoglobulin in serum.
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Serum IgA - monomer
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Secretory IgA (sIgA)
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Dimer (11S)
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J chain
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Secretory Component
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主要可分兩類

1
Serves an effector function st mucous membrane surfaces (main entry sites for most pathogenic organisms).
2
Because it is polymeric, secretory IgA can cross-link large antigens with multiple epitopes
3
Binding of secretory IgA to bacterial and viral surface antigens prevents attachment of the pathogens to the mucosal cells.
5
Provide an important line of defense against pathogens.
4
Complexes of secretory IgA and antigen are easily entrapped in mucus and then eliminated by the ciliated epithelial cells.

〞
A kidney disease that occurs when IgA builds up in your kidneys.
– IgA Nephropathy
Hematuria
啊就...尿出血來啦!

才不是勒!




Minimal
By minghaochen
Minimal
- 112