Hematuria

408510095 陳明皓

Immunoglobulin A

Expressed in mucosal tissues.

Forms dimers after secretion.

Constitutes only 10-15% of the total immunoglobulin in serum.

  • Serum IgA - monomer

  • Secretory IgA (sIgA)

    • Dimer (11S)

    • J chain

    • Secretory Component

主要可分兩類

1

Serves an effector function st mucous membrane surfaces (main entry sites for most pathogenic organisms).

2

Because it is polymeric, secretory IgA can cross-link large antigens with multiple epitopes

3

Binding of secretory IgA to bacterial and viral surface antigens prevents attachment of the pathogens to the mucosal cells.

5

Provide an important line of defense against pathogens.

4

Complexes of secretory IgA and antigen are easily entrapped in mucus and then eliminated by the ciliated epithelial cells.

A kidney disease that occurs when IgA builds up in your kidneys.

– IgA Nephropathy

Hematuria

啊就...尿出血來啦!

才不是勒!

Minimal

By minghaochen