From structure to function: leveraging embedded multimodal imaging to explore brain connectivity

smoia | |
@SteMoia | |
s.moia.research@gmail.com |
Maastricht, 31.10.2024

Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands; physiopy (https://github.com/physiopy)





From structure to function: leveraging embedded multimodal imaging to explore brain connectivity
Maastricht, 31.10.2024
Blood Oxygen Level Dependent (BOLD) signal



Image courtesy of Dimo Ivanov



BOLD signal: "Functional Networks"


Biswal et al., 1995 (Magn. Reson. Med.)





Pearson correlation:
Whole brain functional connectivity







Huang et al., 2018 (Proc. IEEE)



From timeseries to graphs


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From timeseries to graphs


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From timeseries to graphs


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From timeseries to graphs


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From timeseries to graphs


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From timeseries to graphs


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From timeseries to graphs


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Graph Signal Processing





Ortega 2022 (Introduction to Graph signal Processing)
Preti et al. (2019) Nat. Commun.; Huang et al. (2018) Proc. IEEE
Graph Signal Processing: Filtering




Decomposition
to access
"graph" spectral domain



NiGSP is an open development (python) toolbox to apply
Graph Signal Processing on neuroimaging data
It offers a set of function for filter creations, filtering, visualisation,
and metrics computations









Applying Graph Signal Processing: NiGSP




Moia et al. (2023) Zenodo





Preti et al. (2019) Nat. Commun.; Griffa et al. (2022) Neuroimage; Forrer et al. (2024) Biol. Psychiatry

pip install nigsp[all]
nigsp -f timeseries.nii.gz -s sc_mtx.tsv -a atlas.nii.gz --informed-surrogates -n 1000
Moia et al. (2023) Zenodo; based on Preti, Van De Ville (2019) Nat. Commun. and Griffa et al. (2022) Neuroimage
Applying Graph Signal Processing: NiGSP




Thanks to...
That's all folks!

smoia | |
@SteMoia | |
s.moia.research@gmail.com |


...you for the (sustained) attention!
...the MR-methods group @UM

Part of this research is supported by the European Union’s Horizon Europe research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101109770
Find the presentation at:
slides.com/ephraim24/mbic-multimodal-connectivity/scroll



...the MIP:Lab @ EPFL

Any question [/opinions/objections/...]?
From structure to function: leveraging embedded multimodal imaging to explore brain connectivity
By Stefano Moia
From structure to function: leveraging embedded multimodal imaging to explore brain connectivity
CC-BY 4.0 Stefano Moia, 2024. Images are property of the original authors and should be shared following their respective licences. This presentation is otherwise licensed under CC BY 4.0. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/
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